Methods of Execution

Lethal Injection

Though lethal injection has been used for a majority of the executions carried out in the modern era, it is plagued by problematic executions and controversy.

Overview 
 

All states and the fed­er­al gov­ern­ment use lethal injec­tion as their pri­ma­ry method of exe­cu­tion. Jurisdictions use a vari­ety of pro­to­cols typ­i­cal­ly employ­ing one, two, or three drugs. Most three-drug pro­to­cols use an anes­thet­ic or seda­tive, fol­lowed by a drug to par­a­lyze the inmate, and final­ly a drug to stop the heart. The one and two-drug pro­to­cols typ­i­cal­ly use an over­dose of an anes­thet­ic or seda­tive to cause death.

Although the con­sti­tu­tion­al­i­ty of lethal injec­tion has been upheld by the Supreme Court, the spe­cif­ic appli­ca­tions used in states con­tin­ues to be wide­ly chal­lenged pri­or to each exe­cu­tion. Because it is increas­ing­ly dif­fi­cult to obtain the drugs used in ear­li­er exe­cu­tions, states have resort­ed to exper­i­ment­ing with new drugs and drug com­bi­na­tions to car­ry out exe­cu­tions, result­ing in numer­ous pro­longed and painful exe­cu­tions. States are also turn­ing to pre­vi­ous­ly dis­card­ed forms of exe­cu­tion, such as the elec­tric chair and gas cham­ber, in the event that lethal drugs can­not be obtained.

At Issue 
 

Even though the issues sur­round­ing lethal injec­tion are far from set­tled, states are attempt­ing to cut off debate by con­ceal­ing their exe­cu­tion prac­tices under a veil of secre­cy. Recently passed laws bar the pub­lic from learn­ing the sources of lethal drugs being used, mak­ing it impos­si­ble to judge the reli­a­bil­i­ty of the man­u­fac­tur­er or the pos­si­ble expi­ra­tion of these drugs.

What DPI Offers 
 

DPI has state-by-state sum­maries of the meth­ods of exe­cu­tion cur­rent­ly in place and the types of drugs used in each exe­cu­tion in the past ten years. A DPI report cov­ers the exe­cu­tion secre­cy laws that have been imposed in many states. Statements from var­i­ous phar­ma­ceu­ti­cal com­pa­nies bar­ring the use of their drugs in exe­cu­tions are also provided.

News & Developments


News

Mar 18, 2025

Nine Tennessee Death Row Prisoners Challenge State’s One-Drug Lethal Injection Protocol, Citing High Risk of Torturous Death”

Five vials of clear liquid, varying sizes. One is on its side with a syringe in it.

On March 14, 2025, a group of nine death row pris­on­ers in Tennessee filed a law­suit chal­leng­ing the state’s sole use of pen­to­bar­bi­tal in its revised lethal injec­tion pro­to­col, argu­ing it cre­ates a​“high risk of a tor­tur­ous death.” In December 2024, the Tennessee Department of Correction (TDOC) com­plet­ed a mul­ti-year lethal injec­tion pro­to­col review and announced that instead of the pre­vi­ous three-drug pro­to­col, the state would shift to rely on just one drug:…

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News

Feb 24, 2025

Article of Interest: Cato Institute Fellow Critiques Medical Ethics Double Standard Around Executions

In a February blog post, Cato Institute Senior Fellow Jeffrey A. Singer crit­i­cizes the use of med­ical­ized lethal injec­tion, high­light­ing the dou­ble stan­dard under which pro­ce­dures that med­ical pro­fes­sion­als are eth­i­cal­ly barred from car­ry­ing out are not only allowed, but required, of law enforce­ment per­son­nel.​“A doc­tor who inten­tion­al­ly per­forms cru­el and med­ical­ly unjus­ti­fi­able pro­ce­dures that cause pain and suf­fer­ing could face crim­i­nal charges. If…

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News

Jan 23, 2025

Arizona’s Handling of Lethal Injection Drugs Raises Transparency and Viability Concerns

According to inves­tiga­tive report­ing from the AZ Mirror, the Arizona Department of Corrections, Rehabilitation, & Reentry (ADCRR) is stor­ing the state’s sup­ply of pen­to­bar­bi­tal salt, the active ingre­di­ent used in a com­pound­ed form in lethal injec­tion exe­cu­tions, in eight unmarked glass con­tain­ers in a prison refrig­er­a­tor, rais­ing doubts about the drugs’ authen­tic­i­ty and effi­ca­cy. ADCRR has refused to reveal how long it has been in pos­ses­sion of these…

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