Methods of Execution

Lethal Injection

Though lethal injection has been used for a majority of the executions carried out in the modern era, it is plagued by problematic executions and controversy.

Overview 

All death penal­ty states, the mil­i­tary, and the fed­er­al gov­ern­ment autho­rize lethal injec­tion as a method of exe­cu­tion. Jurisdictions use a vari­ety of exe­cu­tion pro­to­cols using one or more drugs. Most three-drug pro­to­cols use an anes­thet­ic or seda­tive, fol­lowed by a drug to par­a­lyze the pris­on­er, and final­ly a drug to stop the heart. One and two-drug pro­to­cols typ­i­cal­ly use an over­dose of an anes­thet­ic or seda­tive, such as pen­to­bar­bi­tal, to cause death.

Although the con­sti­tu­tion­al­i­ty of lethal injec­tion has been upheld by the United States Supreme Court, many of the spe­cif­ic appli­ca­tions are being legal­ly chal­lenged. Because it is increas­ing­ly dif­fi­cult to obtain legal­ly the drugs com­mon­ly used in exe­cu­tions, some states have exper­i­ment­ed with new drugs and dif­fer­ent drug com­bi­na­tions to car­ry out exe­cu­tions, result­ing in pro­longed exe­cu­tions in which pris­on­ers exhib­it­ed symp­toms of pain and dis­tress. The dif­fi­cul­ty obtain­ing drugs for lethal injec­tion has also dri­ven up the costs

Even though the issues sur­round­ing lethal injec­tion are far from set­tled, some states have attempt­ed to cut off debate by con­ceal­ing their exe­cu­tion prac­tices under veils of secre­cy. Laws passed over the past decade explic­it­ly pre­vent the pub­lic from learn­ing the prove­nance of lethal drugs, mak­ing it impos­si­ble to assess their reli­a­bil­i­ty and efficacy.

DPI has com­piled sum­maries of avail­able infor­ma­tion regard­ing the meth­ods of exe­cu­tion cur­rent­ly autho­rized and the drugs used in exe­cu­tions over the past ten years. DPI’s report, Behind the Curtain cov­ers the exe­cu­tion secre­cy laws that have been imposed in many states. Statements from var­i­ous phar­ma­ceu­ti­cal com­pa­nies bar­ring the use of their drugs in exe­cu­tions are also provided.

News & Developments


News

Apr 27, 2026

Department of Justice Releases Memo Calling for Expansion of Federal Death Penalty and New Methods

On April 24, 2026, the Department of Justice’s Office of Legal Policy released a detailed report, Restoring and Strengthening the Federal Death Penalty, call­ing on the Federal Bureau of Prisons (BOP) to rein­state use of a sin­­gle-drug (pen­to­bar­bi­tal) exe­cu­tion pro­to­col, and urg­ing Congress to enact sweep­ing leg­isla­tive changes that would expand the reach and speed of the fed­er­al death penal­ty. Alongside the release of the report, DOJ announced that it has direct­ed BOP to…

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News

Feb 23, 2026

Twenty Years Since the Last Scheduled Execution in California and a Focus on the Participation of Physicians in Executions

February 21, 2006, a California court’s deci­sion effec­tive­ly halt­ed the planned exe­cu­tion of Michael Angelo Morales, mark­ing the start of California’s 20-year mora­to­ri­um on exe­cu­tion sched­ul­ing and throw­ing into the spot­light the ten­sion between physi­cian par­tic­i­pa­tion in exe­cu­tions and their pledge to show​“the utmost respect for life.” > The events sur­round­ing Morales’s impend­ing fate brought to the sur­face the long-run­n­ing schism between law and medicine,…

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News

Feb 04, 2026

Bipartisan Support Defeats Indiana House Bill to Add Firing Squad as Execution Method

A bipar­ti­san group of 19 Republicans and 28 Democrats nar­row­ly defeat­ed a mea­sure to add the fir­ing squad as an exe­cu­tion method in an Indiana House floor vote on January 28, 2026. HB 1119 received 48 in favor and 47 against, falling three votes short of pas­sage, with two leg­is­la­tors not vot­ing and three absent. Although the mea­sure could have been brought for a sec­ond vote before February 2, it was not. A sim­i­lar Senate bill (SB 11) to add the fir­ing squad stalled in…

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News

Jan 27, 2026

Death-Sentenced Prisoner Christa Pike Files Religious Challenge to Tennessee’s Execution Protocol

Christa Pike, the only woman on Tennessee’s death row, has filed a law­suit in the Davidson County Chancery Court chal­leng­ing the state’s lethal injec­tion pro­to­col, assert­ing it vio­lates her con­sti­tu­tion­al rights and con­flicts with her reli­gious beliefs. The state’s new exe­cu­tion pro­to­col relies sole­ly on pen­to­bar­bi­tal to induce res­pi­ra­to­ry and car­diac arrest, rather than the for­mer three-drug cock­tail. Ms. Pike argues that Tennessee’s lim­i­ta­tion on clergy,…

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News

Jan 21, 2026

New Autopsy Report Renews Concerns about Arizona’s Execution Protocol

An autop­sy of Richard Djerf, who was exe­cut­ed in Arizona in October 2025, has renewed con­cerns about the state’s lethal injec­tion exe­cu­tion pro­to­col and the state’s efforts to address long­stand­ing exe­cu­­tion-relat­ed con­cerns. Mr. Djerf was con­vict­ed for the September 1993 mur­ders of four mem­bers of the Luna fam­i­ly in Phoenix. The autop­sy, con­duct­ed by Pinal County Chief Medical Examiner Dr. John Hu, estab­lished for the first time that med­ical personnel encountered…

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